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Why Shar Pei Dogs Have So Many Wrinkles




Researchers have discovered the origin of the mucinosis present in Shar Pei dogs, a hereditary disorder responsible for the characteristic wrinkles found in this breed. The research report appears in the journals Veterinary Dermatology and Journal of Heredity. The report details the genetic alteration in this breed which multiplies the activity of an enzyme responsible for an excessive production of hyaluronic acid, a substance which gathers under the skin and produces wrinkles.


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